Spotlight
| FY12 Spending Debate Comes to a Close |
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Congress completed, and the President signed into law, the FY12 appropriations bill. The $915 billion spending bill wraps up the remaining nine appropriations measures. The bill provides funding for programs at the Department of Health and Human Services, including the National |
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| Rep. Rush Holt’s (D-NJ) Editorial in Most Recent Science |
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Science 16 September 2011: Dueling Visions for Science
Rush Holt A |
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New Clues to Parkinson's Disease from an Unlikely Source - 5/21/08
Dr. Susan Lindquist
Whitehead Institute for Biomedical Research/Massachusetts Institute of Technology
What do "mad cows," people with neurodegenerative diseases, and yeast cells growing profusely on a deadly antibiotic have in common? They are all experiencing the consequences of misfolded proteins. These proteins must fold into just the right shape to do their jobs properly.
Dr. Lindquist explaines what happens when proteins misfold. In humans, the consequences of protein misfolding can be deadly, leading to devastating neurodegenerative diseases such as Parkinson's and Huntington's disease. Lindquist has been studying yeast to screen for genes that may improve the ill effects caused by misfolding proteins in Parkinson's disease. The genetic pathways she is identifying represent promising targets for the development of new drugs that may lead to innovative treatments for diseases such as Parkinson's.
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